Phages are ubiquitous in bacteria, including clinical Staphylococcus aureus, where Sfi 21/Sa3 phages often integrate into the hlb gene, which encodes Hlb sphingomyelinase.This WILD OIL OF OREGANO integration acts as a rapid regulatory switch for Hlb production.Our findings suggest that Sfi 21/Sa3 prophages and Hlb activity influence S.aureus fitnes
BackgroundEnvironmental vinyl chloride (VC) exposure may result in serious acute and chronic dermatological conditions.Because existing literature largely focuses on exposures in occupational settings, a gap persists in our understanding of the medical consequences of large-scale chemical spills.ObjectiveThis study aims to examine the potential der
Whether epithelial-mesenchymal transition (EMT) is always linked to increased tumorigenicity is controversial.Through microRNA (miRNA) expression profiling of mammary epithelial cells overexpressing Twist, Snail or ZEB1, we identified miR-100 as a novel EMT inducer.Surprisingly, miR-100 inhibits the tumorigenicity, motility and invasiveness of mamm
Familial spinal muscular atrophy (FSMA) associated with the vesicle-associated membrane protein-associated protein B (VAPB) gene is a rare autosomal dominant disease with late onset and slow progression.We studied 10 of 42 patients from 5 families by taking clinical histories and performing physical exams, Custom Shape Warm LED Night Light electrop
A new interpretation of the Middle Jurassic-Early Cretaceous paleogeographic evolution of the NW sector of the Latium-Abruzzi carbonate platform facing the Umbria-Marche Basin is proposed, based on Monte Giano area (central Apennines, Italy).During Late Triassic-early Bajocian time, the area was characterized by shallow water sedimentation.Inner an